A Comprehensive Framework to Reinforce Evidence Synthesis Features in Cloud-Based Systematic Review Tools

Systematic reviews are powerful methods used to determine the state-of-the-art in a given field from existing studies and literature. They are critical but time-consuming in research and decision making for various disciplines. When conducting a review, a large volume of data is usually generated from relevant studies. Computer-based tools are often used to manage such data and to support the systematic review process. This paper describes a comprehensive analysis to gather the required features of a systematic review tool, in order to support the complete evidence synthesis process. We propose a framework, elaborated by consulting experts in different knowledge areas, to evaluate significant features and thus reinforce existing tool capabilities. The framework will be used to enhance the currently available functionality of CloudSERA, a cloud-based systematic review tool focused on Computer Science, to implement evidence-based systematic review processes in other disciplines.This research was funded by the Spanish Research Agency (Agencia Estatal de Investigacion) with ERDF funds grant number TIN2017-85797-R (VISAIGLE project). The research stay of T. Person in the SFU was funded by Erasmus+ KA107 grant number 2017-1-ES01-KA107-037422. The APC was funded by the VISAIGLE project

Superhydrophobic supported Ag-NPs@ZnO-nanorods with photoactivity in the visible range

In this article we present a new type of 1D nanostructures consisting of supported hollow ZnO nanorods (NRs) decorated with Ag nanoparticles (NPs). The 3D reconstruction by high-angle annular dark field scanning transmission electron microscopy (HAADF-STEM) electron tomography reveals that the Ag NPs are distributed along the hollow interior of the ZnO NRs. Supported and vertically aligned Ag-NPs@ZnO-NRs grow at low temperature (135 °C) by plasma enhanced chemical vapour deposition on heterostructured substrates fabricated by sputtered deposition of silver on flat surfaces of Si wafers, quartz slides or ITO. The growth mechanisms of these structures and their wetting behavior before and after visible light irradiation are critically discussed. The as prepared surfaces are superhydrophobic with water contact angles higher than 150°. These surfaces turn into superhydrophilic with water contact angles lower than 10° after prolonged irradiation under both visible and UV light. The evolution rate of the wetting angle and its dependence on the light characteristics are related to the nanostructure and the presence of silver embedded within the ZnO NRs. ÂEuropean Union NMP3-CT-2006- 032583Ministerio de Ciencia e Innovación MAT2010-21228, MAT2010-18447, CSD2008-00023Junta de Andalucía P09-TEP-5283, CTS-518

One-reactor plasma assisted fabrication of ZnO@TiO2 multishell nanotubes: assessing the impact of a full coverage on the photovoltaic performance

This paper addresses the fabrication of vertically aligned ZnO@TiO2 multishell nanotubes by a combined full vacuum-plasma approach at mild temperatures. The growth is carried out within the premises of a one-reactor approach, i.e. minimizing the number of vacuum chambers and sample transferences. In this way, the interface between ZnO and TiO2 is fully preserved from humidity thus increasing ZnO durability and stability. These nanostructures are studied by scanning electron microscopy (SEM), scanning transmission electron microscopy (STEM) and energy dispersive X-ray spectroscopy in STEM (EDX-STEM). High density one-dimensional arrays of these nanotubes formed on FTO substrates are applied as photoanode in a dye-sensitized solar cell (DSC). The evolution of the dye adsorption capacity and solar cells parameters are explored as a function of the crystallinity and thickness of the TiO2 shell. The results show the critical effect of a full coverage by TiO2 of ZnO core to explain the mixed results found in the literature.Junta de Andalucia FQM 1851 FQM-2310España Mineco Agencia Estatal de Investigación MAT2016–79866-R MAT2013–42900-P MAT2013– 47192-C3-3-RMINECO-CSIC 201560E055Marie Skłodowska-Curie Actions H2020-MSCA-IF-2014PlasmaPerovSol grant 66148

Influence of the COVID-19 Pandemic on Medication Reconciliation in Frail Elderly People at Hospital Discharge: Perception of Healthcare Professionals

The current demographic panorama in Spain corresponds to an aging population; this situation is characterized by the need to care for an elderly population, which contains polymedicated and pluripathological individuals. Polymedication is a criterion of frailty in the elderly and a risk factor for mortality and morbidity due to the increased risk of drug interactions and medication errors. There are numerous studies that measure reconciliation at hospital discharge and at admission, and even the methodology of reconciliation, but we have not found many studies that measure reconciliation in the context of the COVID-19 pandemic from the point of view of health professionals regarding difficulties and the strategies carried out, which is essential to begin to glimpse solutions. Methods. This was a qualitative study based on 21 in-depth interviews and two discussion groups, conducted between January and April 2021 (13 nurses and 8 doctors, in rural and urban areas). The discourse was analyzed according to the Taylor–Bodgan model and processed using Atlas.ti software. Results. The areas altered by the health crisis were access to patients, their reconciliation of medication, and changes in the care modality, including the greater use of telephone communication, changes in work organization, and time dedicated to patient care and family work. Difficulties encountered during COVID-19: change in medication format, the specific characteristics of the patient and their pathologies, and difficulties arising from communication with the patient and their family. The strategies applied: the collaboration of home assistants and caregivers, emphasis on patient–health professional communication, and the use of Information and Communication Technologies (ICT). Conclusion. The discharge was interrupted by the health crisis caused by COVID-19, in terms of both the traditional access of patients and by the remote care modalities generated by telemedicin

Nanostructured Ti thin films by magnetron sputtering at oblique angles

The growth of Ti thin films by the magnetron sputtering technique at oblique angles and at room temperature is analysed from both experimental and theoretical points of view. Unlike other materials deposited in similar conditions, the nanostructure development of the Ti layers exhibits an anomalous behaviour when varying both the angle of incidence of the deposition flux and the deposition pressure. At low pressures, a sharp transition from compact to isolated, vertically aligned, nanocolumns is obtained when the angle of incidence surpasses a critical threshold. Remarkably, this transition also occurs when solely increasing the deposition pressure under certain conditions. By the characterization of the Ti layers, the realization of fundamental experiments and the use of a simple growth model, we demonstrate that surface mobilization processes associated to a highly directed momentum distribution and the relatively high kinetic energy of sputtered atoms are responsible for this behaviourJunta de Andalucía P12-FQM- 2265Ministerio de Ciencia e Innovación CSD2008- 00023, MAT2013-42900-P, MAT2013-40852-R, MAT2014-59772-C2-1, MAT2011- 2908

Vacuum template synthesis of multifunctional nanotubes with tailored nanostructured walls

A three-step vacuum procedure for the fabrication of vertical TiO2 and ZnO nanotubes with three dimensional walls is presented. The method combines physical vapor deposition of small-molecules, plasma enhanced chemical vapor deposition of inorganic functional thin films and layers and a postannealing process in vacuum in order to remove the organic template. As a result, an ample variety of inorganic nanotubes are made with tunable length, hole dimensions and shapes and tailored wall composition, microstructure, porosity and structure. The fabrication of multishell nanotubes combining different semiconducting oxides and metal nanoparticles is as well explored. This method provides a feasible and reproducible route for the fabrication of high density arrays of vertically alligned nanotubes on processable substrates. The emptying mechanism and microstructure of the nanotubes have been elucidated through SEM, STEM, HAADF-STEM tomography and energy dispersive X-ray spectroscopy. In this article, as a proof of concept, it is presented the straightforward integration of ZnO nanotubes as photoanode in a photovoltaic cell and as a photonic oxygen gas sensorJunta de Andalucia TEP8067 FQM-6900 FQM 1851 P12-FQM-2265España Mineco CONSOLIDER-CSD 2008-00023 MAT2013-40852-R MAT2013-42900-P MAT2013-47192-C3-3-R RECUPERA 2020Unión Europea FP/2007-2013 312483 - ESTEEM2 291522 - 3DIMAGE REGPOT-CT-2011-285895-Al-NANOFUNC

Growth regimes of porous gold thin films deposited by magnetron sputtering at oblique incidence: from compact to columnar microstructures

Growth regimes of gold thin films deposited by magnetron sputtering at oblique angles and low temperatures are studied from both theoretical and experimental points of view. Thin films were deposited in a broad range of experimental conditions by varying the substrate tilt angle and background pressure, and were analyzed by Field Emission Scanning Electron Microscopy (FESEM) and Grazing Incidence Small-Angle X-ray Scattering (GISAXS) techniques. Results indicate that the morphological features of the films strongly depend on the experimental conditions, but can be categorized within four generic microstructures, each of them defined by different bulk geometrical patterns and pore percolation depth and connectivity. With the help of a growth model, a microstructure phase diagram has been constructed where the main features of the films are depicted as a function of experimentally controllable quantities, finding a good agreement with the experimental results in all the studied cases.Junta de Andalucía P09-CTS- 5189, TEP5283, P10-FQM-6900Comunidad de Madríd S2009/MAT–1726Ministerio de Economía y Competitividad MAT2011-29194-C02-01, CSD2008-00023, MAT2008-06652, MAT2010-21228, MAT2010-1844

Influence of plasma-generated negative oxygen ion impingement on magnetron sputtered amorphous SiO2 thin films during growth at low temperatures

Growth of amorphous SiO2 thin films deposited by reactive magnetron sputtering at low temperatures has been studied under different oxygen partial pressure conditions. Film microstructures varied from coalescent vertical column-like to homogeneous compact microstructures, possessing all similar refractive indexes. A discussion on the process responsible for the different microstructures is carried out focusing on the influence of (i) the surface shadowing mechanism, (ii) the positive ion impingement on the film, and (iii) the negative ion impingement. We conclude that only the trend followed by the latter and, in particular, the impingement of O- ions with kinetic energies between 20 and 200 eV, agrees with the resulting microstructural changes. Overall, it is also demonstrated that there are two main microstructuring regimes in the growth of amorphous SiO2 thin films by magnetron sputtering at low temperatures, controlled by the amount of O2 in the deposition reactor, which stem from the competition between surface shadowing and ion-induced adatom surface mobilityMinisterio de Innovación español-MAT 2007-65764Ministerio de Innovación español (CONSOLIDER INGENIO 2010)-CSD2008-00023Junta de Andalucía-TEP2275, TEP5283, P07-FQM-03298 y P10-FQM-690

Low temperature plasma processing of platinum porphyrins for the development of metal nanostructured layers

This article establishes the bases for a vacuum and plasma supported methodology for the fabrication at mild temperatures of nanostructured platinum in the form of porous layers and nanocolumns using platinum octaethylporphyrin as precursor. In addition, the application of these materials as tunable optical filters and nano-counterelectrodes is proved. On one hand, the transparency in the ultraviolet-visible-near infrared range can be adjusted precisely between 70% and 1% by tuning the deposition and processing conditions, obtaining a high spectral planarity. Deviations of the spectra from an ideal flat filter are below 4%, paving the way to the fabrication of neutral density filters. The transparency limit values yield a sheet resistivity of ¿1350 and 120 ¿ ¿-1, respectively. On the other hand, the catalytic properties of the nanostructures are further demonstrated by their implementation as counterelectrodes of excitonic solar cells surpassing the performance of commercial platinum as counterelectrode in a 20% of the overall cell efficiency due to simultaneous enhancement of short-circuit photocurrent and open-circuit photovoltage. One of the most interesting features of the developed methodology is its straightforward application to other metal porphyrins and phthalocyanines readily sublimable under mild vacuum and temperature conditions.Junta de AndaluciaTEP8067 FQM-6900 FQM 1851 P12-FQM-2265España MinecoMAT2013-40852-R MAT2013-42900-P MAT2013-47192-C3-3-RMAT2016-79866-RMINECO-CSIC 201560E055

Heterozygous Arrhythmogenic Cardiomyopathy-desmoplakin Mutation Carriers Exhibit a Subclinical Cutaneous Phenotype with Cell Membrane Disruption and Lack of Intercellular Adhesion

Genetic variants that result in truncation in desmoplakin (DSP) are a known cause of arrhythmogenic cardiomyopathy (AC). In homozygous carriers, the combined involvement of skin and heart muscle is well defined, however, this is not the case in heterozygous carriers. The aim of this work is to describe cutaneous findings and analyze the molecular and ultrastructural cutaneous changes in this group of patients. Four women and eight men with a mean age of 48 ± 14 years were included. Eight met definitive criteria for AC, one was borderline and three were silent carriers. No relevant macroscopic changes in skin and hair were detected. However, significantly lower skin temperature (29.56 vs. 30.97 ◦C, p = 0.036) and higher transepidermal water loss (TEWL) (37.62 vs. 23.95 g m 2 h 1, p = 0.028) were observed compared to sex- and age-matched controls. Histopathology of the skin biopsy showed widening of intercellular spaces and acantholysis of keratinocytes in the spinous layer. Immunohistochemistry showed a strongly reduced expression of DSP in all samples. Trichogram showed regular nodules (thickening) compatible with pseudomonilethrix. Therefore, regardless of cardiac involvement, heterozygous patients with truncation-type variants in DSP have lower skin temperature and higher TEWL, constant microscopic skin involvement with specific patterns and pseudomonilethrix in the trichogram.Andalusian Society of Cardiology with a “beca de Investigación general